Dr. Brinkley received a B.A. in mathematics from Amherst College in 1970, an M.D. from the University of Washington in 1974, and a Ph.D. in medical computer engineering from Stanford University in 1984. He was a Postdoctoral Fellow at the University of Washington, Department of Bioengineering from 1974-77, and a Research Associate in the Stanford Department of Computer Science from 1984-1988. He joined the faculty of the Department of Biological Structure in 1988. He is currently a Research Professor in Biological Structure, joint with the Division of Biomedical and Health Informatics of the Dept of Medical Education, and adjunct with the Dept of Computer Science and Engineering. He is a fellow of the American College of Medical Informatics, and is on the editorial board of the Journal of the American Medical Association and the Journal of Biomedical Informatics. He is co-director (with Cornelius Rosse) of the Structural Informatics Group  at the University of Washington, http://sig.biostr.washington.edu.

He coined the term Structural Informatics in 1990 as a branch of Medical Informatics having to do with the application of computer and information technology to problems in structural biology at levels ranging from organs to molecules. Within the UW Structural Informatics Group the long range goals are to develop methods for representing information about the physical organization of the body, and to use these representations to develop a “structural information framework” for organizing biomedical knowledge.  Current projects  include: 1) anatomical enhancements to the National Library of Medicine’s Unified Medical Language System, 2) a symbolic foundational model of anatomy, 3) the Digital Anatomist information system, and 4) the University of Washington Human Brain Project.