HOME	MEBI 534 , Autumn 2008 Biology and Informatics
	Physiology: Informatics  Assignment A.  Read the following papers   Hunter 2003, "Integration from Proteins to Organs: the Physiome Project". Gennari 2007, "Integration of multi-scale biosimulation models via light-weight semantics" Optional: Cook2008, "Bridging biological ontologies and biosimulation: The Ontology of Physics for Biology" B. Provide written answers to the following questions, to be turned in prior to the Wed class, as per these instructions. These questions are based on the papers assigned above. 1. What is the physiome project? 2. What is meant by the term "continuum models" in the Hunter paper, and how is this concept used in simulating organ function? 3. What is an ApplModel ontology? 4. What is the difference between the ApplModel Ontology and the Ontology of Physics for Biology (OPB)? 5. How will the ApplModel framework facilitate the merging of two or more separate biosimulation models?
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