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Systems
Biology: Assignment
A. Read the following
Ideker2001 Systems Biology
Louie
2006 Data integration systems
B. Provide written answers to the following questions, to be
turned in prior to the Wed class, as per these instructions.
- What is discovery science, and how does it
differ from hypothesis-driven
science?
- In one paragraph describe the framework
for systems biology
proposed by Ideker.
- How was the framework for systems biology
applied in order
to understand the regulatory network controlling galactose utilization
in
yeast?
- Where do the data integration methods
described in the Louie
paper fit into the systems biology framework proposed by Ideker?
- Describe the main data integration
methods: data warehouse,
database federation, database federation with mediated schema, peer
data
management.
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