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The University of Washington Structural Informatics Group (SIG) is an interdisciplinary team of computer scientists, engineers and biologists, which is part of the Department of Biological Structure and the Division of Biomedical and Health Informatics, Department of Medical Education and Biomedical Informatics, with strong ties to the Department of Computer Science and Engineering.

The emphasis of SIG is on the development of methods for representing, managing, visualizing and utilizing information about the physical organization of the body. The group was originally called the Biological Structure Computer Graphics Group, under the direction of John Sundsten and John Prothero. It later became the Digital Anatomist Program, under the direction of Cornelius Rosse. It is currently directed by Jim Brinkley. Linda Shapiro and Dan Cook are co-directors.

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